2019-06-24 09:30:192025-05-22 01:21:38
locus
BSU22750
BSU_22750
outlinks
bsu
BSU22750
BSU_22750
Gene
Phenotypes of a mutant
essential [http://www.ncbi.nlm.nih.gov/pubmed/?term=12682299 according to Kobayashi et al. ]; however, inactivation reported by [http://www.ncbi.nlm.nih.gov/pubmed/?term=26735940 Meeske et al. ] and [http://www.ncbi.nlm.nih.gov/pubmed/?term=20511502 Block et al. ]
inactivation of ''[[gene|menH]]'' reduces sporulation efficiency to 12.7% that of wild type cells [Pubmed|26735940]
essential [http://www.ncbi.nlm.nih.gov/pubmed/?term=12682299 according to Kobayashi et al.]; however, inactivation reported by [http://www.ncbi.nlm.nih.gov/pubmed/?term=26735940 Meeske et al.] and [http://www.ncbi.nlm.nih.gov/pubmed/?term=20511502 Block et al.]
inactivation of ''[[gene|menH]]'' reduces sporulation efficiency to 12.7% that of wild type cells [Pubmed|26735940]
defective in biofilm formation [pubmed|31420537]
The protein
Catalyzed reaction/ biological activity
S-adenosyl-L-methionine + demethylmenaquinol = s-adenosyl-L-homocysteine + menaquinol (according to Swiss-Prot)
2-demethylmenaquinol + S-adenosyl-L-methionine --> menaquinol + H+ + S-adenosyl-L-homocysteine (according to UniProt)
The protein
Protein family
[SW|Methyltransferase superfamily] (according to UniProt)
MenG/UbiE family (single member, according to UniProt)
[SW|Methyltransferase superfamily] (according to UniProt)
[SW|class I-like SAM-binding methyltransferase superfamily] (according to UniProt)
References
The protein
[SW|Domains]
[SW|AB hydrolase-1 domain] (aa 26-259) (according to InterPro)
Expression and Regulation
additional information
highly expressed at high iron concentrations [pubmed|31420537]